Summary

The James Orengo Lab seeks a dedicated and motivated research technician II to be a part of the labs work on exploring novel therapeutics in spinocerebellar ataxias (SCAs). The position entails joining a team of scientist to assist and manage experiments using mouse models and human cell culture models. 

This is a full time position and will be onsite only. 

Job Duties

• Assist in the management of a small-medium sized mouse colony. 
• Carefully genotype mice of various genetic backgrounds.
  • This include collecting a small amount of tissue and extracting DNA followed by PCR analysis. Careful record keeping is imperative to track the genotype of each mouse in the colony.
• Collect tissue from mouse models for analysis.
• Collect nervous system tissue from mouse models, perserve it and section it on slide for staining.
• Analyze stained tissue under the microscope for features of disease.
• Perform drug screening on human cell culture system.
• Manage a set of experiments to apply these drugs at various concentrations to SCA cell culture models and assess for rescue of disease using cell based assays and imuno-histochemistry microscopy.

Minimum Qualifications

• Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
• No experiene required.

Preferred Qualifications

• Work in a previous lab with rodent models is preferred.