Summary

The laboratory of Dr. Mingshan Xue (https://www.bcm.edu/research/labs/mingshan-xue) in the Jan and Dan Duncan Neurological Research Institute (NRI) is seeking applicants for a staff scientist position. The NRI is dedicated to research aimed at understanding normal brain function and the pathogeneses of neurological disorders. Located in the Texas Medical Center, the NRI provides a vibrant environment to facilitate collaborations between labs and promote dynamic interactions between basic researchers and clinicians.

Job Duties

• Design and conduct research studies to investigate the synaptic mechanisms of cortical circuits in mice, including dysfunctions of cortical circuits in novel mouse models of neurodevelopmental disorders.
• Independently plan, design and perform research experiments to investigate synaptic mechanisms that govern cortical circuit function in mice using two-photon imaging electrophysiology, optogenetics, molecular genetics, and animal behaviors experiments.
• Develop and characterize novel mouse models of neurodevelopmental disorders and evaluate dysfunctions of cortical circuits.
• Analyze, interpret, and document data using appropriate methods. Maintains detailed laboratory notebooks and experimental records.
• Work collaboratively with other lab members to experimentally support projects and ensure that projects move forward.
• Assist PI in overseeing logistics of projects in the lab.
• Responsible for management of transgenic mouse colony and ensure compliance with institutional and regulatory requirements for animal research.
• Conduct literature searches to identify optimal scientific protocols to address experimental questions. 
• Develop research techniques when necessary for specific research projects. 
• Coordinate the activities of less experienced research staff.
• Train new lab members in laboratory processes and specific research techniques. 
• Perform other job related duties as assigned.

Minimum Qualifications

• Doctoral Degree. Experience may not be substituted in lieu of degree.
• Three years of post doctoral research experience.

Preferred Qualifications

• Preferred applicants should have a strong research record in one or more of the following areas: in vivo two-photon imaging, in vivo electrophysiology, and animal behavior.
• While previous experience in neuroscience is desired, we are also interested in individuals with a broad range of expertise. Applicants with a background in math, physics, or computer science are encouraged to apply.