Title:  Staff Scientist-Biochemist/Molecular Biologist/Geneticist

Division:  Pathology
Schedule:  Monday - Friday, 8:00 a.m. - 5:00 p.m.
Work Location:  Texas Medical Center, Houston, TX
Salary Range:  Up to $65,000
FLSA Status:  Exempt
Requisition ID:  2442

The Center for Drug Discovery (https://www.bcm.edu/research/centers/drug-discovery) is a strategic research center established at Baylor College of Medicine in Houston, Texas. The mission of the Center for Drug Discovery is to establish novel discovery technologies that enable rapid and cost-effective drug discovery within the academic community. We are seeking highly skilled and motivated scientists with expertise in biochemistry, recombinant protein production/purification, biochemical assay methodologies, molecular biology, and/or mouse genetics to join the Center for Drug Discovery. Central to our vision is the continued establishment of a small-molecule discovery platform using a DNA-encoded chemistry approach.

The team, led by scientists with drug discovery and genetics experience in academia and the pharmaceutical and biotech industry, is looking to recruit additional biochemists, molecular biologists, and geneticists. Baylor College of Medicine is located in the world-renowned Texas Medical Center and offers a highly interactive environment and a strong infrastructure for research and career development.

Job Purpose

The position is reserved for career researchers and is intended to be utilized after completing at least three years of Postdoctoral research.

Job Duties
  • Participate in early stage drug discovery in collaboration with scientists within the academic community, with a goal of bringing new treatments to patients with unmet medical needs.
  • Contribute to multidisciplinary lead-finding project teams by engaging in the following state-of-the art activities: production, purification, and/or testing of recombinant proteins; screening of DNA-encoded chemical libraries; evaluation of compounds for efficacy in vitro (biochemical and cell-based assays) and in vivo; validation of targets using mouse genetics; and/or generation of DNA vectors.
  • Plan, direct and conduct research experiments.
  • Evaluate and analyze data.
  • Develop research techniques and perform applications required for specific research projects.
  • May conduct literature searches and summarize information in an appropriate format for a particular study.
  • Document results of experiments and report to principal investigators.
  • May supervise, schedule and coordinate the activities of less experienced research staff.
Minimum Qualifications


Required: Doctoral Degree. Experience may not be substituted in lieu of degree.


Required: Three years of post doctoral research experience.

Preferred Qualifications
  • PhD in biochemistry, molecular biology, genetics, or a related discipline. Experience may not be substituted in lieu of degree.
  • 3 years of postdoctoral research experience, preferred >4 years of hands-on laboratory experience in biochemistry, recombinant protein technology, molecular biology, mouse genetics, and/or a related field and a track record of quality publications and/or patents in these areas.
  • Experience with one or more of the following:  protein production and purification; molecular biology and vector construction; next generation sequencing technologies and data analysis; CRISPR/Cas9; and/or generation and analysis of mouse knockouts.
  • A strong track record with excellent interpersonal skills and ability to work in a team environment.
FLSA Status






Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.