Summary

The Restoring Joint Health and Function to Reduce Pain (RE-JOIN) consortium is a large, transdisciplinary team science effort that brings scientists from multiple institutions together to better understand the origins of joint pain in diseases such as osteoarthritis. At BCM, the RE-JOIN team consists of five research groups, including the Lee lab, that have joined forces to tackle this research question. We are searching for a Research Technician III to join our team to help us characterize the molecular and cellular changes that mediate pain in the knee joint. The Research Technician III will be responsible for performing exercise and behavioral experiments with mouse models of joint disease. In addition, they will perform tissue clearing and 3D imaging experiments of mouse knee joints. This includes, but is not limited to, tissue collection, fixation, decalcification, tissue clearing, immunostaining, and whole-mount 3D imaging using lightsheet fluorescence microscopy.

For more information about the Lee lab, please visit https://www.bcm.edu/research/faculty-labs/brendan-lee-lab. 
For more information about the RE-JOIN consortium, please visit https://heal.nih.gov/research/preclinical-translational/restoring-joint-health-function-reduce-pain. 

Job Duties

• Conducts tissue clearing and whole-mount 3D imaging experiments.
• Conducts exercise and behavioral experiments.
• Performs tissue clearing on knee joints from various mouse models of joint diseases.
• Optimizes whole-mount in situ histochemistry protocols for cleared mouse knee joints.
• Optimizes and performs post-aquisition image analyses.
• Plans and conducts exercise experiments (treadmill) and behavioral experiments (Von Frey).
• Supports tissue collections (includes perfusion).

Minimum Qualifications

• Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
• One year of relevant experience.

Preferred Qualifications

• Master's degree in basic science or a related field.
• Background in tissue clearing and 3D imaging.
• Experience working with mouse models.