Summary

Become an active member of a research team investigating neurodegenerative diseases, including Alzheimer’s disease and Frontotemporal Dementia. Provide responsible technical assistance in support of research projects by completing assignments requiring a basic knowledge of fundamental techniques and practices related to molecular biology and genetics, working under minimal supervision by a higher-level research staff member.

Seeking a highly motivated, responsible, and organized individual to join a research team focused on understanding the genetics and pathogenesis of Alzheimer’s  disease and related disorders. The individual will participate in studies directed by Dr. Cristian Lasagna-Reeves in the Department of Neurology. The research integrates experimental genetic approaches using genetic mouse models as well as direct study of human iPSC-neurons. The research technician will assist members of the research team in the conduct of experiments. They may additionally be responsible for the handling of routine mouse colony maintenance and ordering lab supplies.  The successful applicant will perform additional duties related to the ongoing research and management efforts of the laboratory. Excellent time management, communication and organizational skills are essential to collect, analyze and appropriately document experimental results. Training in specialized research methods will be provided. 

Job Duties

• Help prepare and perform research experiments; evaluate and analyze data; and document results.
• Perform routine genetic, biochemical, and molecular biology techniques such as cell culture, Western blotting, ELISA, and DNA cloning.
• Perform mouse genetic experiments, including assisting with upkeep of colonies, crossing of specific mouse strains, and genotyping.
• Differentiation and management of iPSC-neurons.
• Maintain detailed records of research activities, including study protocols and records of results. 
• Conduct literature searches and summarize information in an appropriate format for a particular study. 
• Order laboratory supplies and equipment. 
• Assist with cleaning, and maintaining the laboratory area in a neat orderly condition. 
• Performs other job related duties as assigned.

Minimum Qualifications

• Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
• No experience reqquired.