Summary

The Jorgez Laboratory in the Department of Urology at Baylor College of Medicine is seeking a highly motivated Postdoctoral Fellow PhD to join an NIH-funded research program investigating the molecular and developmental mechanisms underlying testicular dysfunction and infertility in a Wnt4 conditional knockout (Wnt4-cKO) mouse model. This position offers the opportunity to work at the interface of developmental biology, reproductive endocrinology, and cutting-edge spatial and 3D imaging technologies, within a collaborative, well-resourced research environment in the Texas Medical Center.

Baylor College of Medicine typically follows similar to the NIH stipulated stipend guidelines for Postdoctoral Associates.

Job Duties

• Designs and executes experiments using mouse models that includes breeding colony management and genotyping.
• Performs advanced 3D and spatial imaging (confocal, LSFM, Xenium spatial transcriptomics) and associated computational image analysis.
• Conducts cellular and molecular assays including, immunohistochemistry, proteomic profiling, and tissue-derived cell culture-based functional studies.
• Analyzes, interprets, and presents complex multimodal datasets integrating imaging, transcriptomic, and proteomic data.
• Prepares manuscripts for peer-reviewed publication and contribute to grant progress reports and future funding applications.
• Maintains reagents and supply for experiments.
• Teaches techniques, procedures, and experimental design to other members of the lab.
• Communicates research results in group meetings, national or international conferences.
• Plans, directs, and conducts research experiments.
• Develops research techniques and perform applications required for specific research projects
• Perform other job-related duties as assigned.

Minimum Qualifications

• Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Experience with advanced 3D imaging modalities (light sheet fluorescence microscopy, confocal microscopy) and/or spatial transcriptomics platforms (e.g., Xenium, Visium).
• Background in male reproductive biology, testicular development, or endocrinology.
• Experience with bioinformatic analysis of transcriptomic or proteomic datasets.
• Experience with animal surgical techniques (e.g., orchidopexy models).
• Experience working on the Wnt/Bcatenin signaling pathway.