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Title:  Postdoctoral Associate

Division:  Molecular and Human Genetics
Schedule:  Monday - Friday, 8 am - 5 pm
Work Location:  Texas Medical Center, Houston, TX
Salary Range:  $54,540
FLSA Status:  Exempt
Requisition ID:  7942

Summary

The Tran lab in the Department of Molecular and Human Genetics is seeking a talented and motivated Postdoctoral Associate to lead projects that will examine the molecular mechanisms of neurodegeneration in optic neuropathies.  The successful candidate will be applying a variety of genetic and single-cell genomic approaches to characterize how neuronal cell types are affected in disease states and probe the key regulators of neuronal survival and growth.  They will be given the opportunity to pursue a research direction of their choosing in one of several research areas that are currently being developed in the lab including:

• Applying single-cell genomic and epigenomic approaches to study degeneration in glaucoma at tissue scale with cellular resolution 
• Mechanistic characterization of genetic targets that promote neuroprotection and axon regeneration 
• Development and high-throughput molecular phenotyping of disease-relevant animal and/or human ipSC-derived models for neurodevelopmental and neurodegenerative disorders 

 

BCM is centrally situated in Houston in the Texas Medical Center, the largest biomedical research center in the world, offering exceptional collaborative opportunities and resources. The Molecular and Human Genetics department consistently ranks nationally among the top genetics departments for NIH funding.  The Postdoctoral Associate will have access to BCM's world-class advanced technology cores, animal facilities, and high-performance computational resources to conduct their experiments. 

 

Dr. Tran has been a project leader on several single-cell RNA-seq studies that have collectively established a comprehensive molecular atlas of mouse retinal cell types and assessed their type-specific responses to axonal injury.  The postdoctoral fellow will benefit from access to scRNA-seq data from several hundred thousand retinal neurons and work in a lab with expertise in these approaches.

 

The Postdoctoral Associate will design and conduct experiments and analyze results under the guidance of the PI.  Specific experimental duties will depend on the research topic of choice but will be expected to cover a broad range of molecular and genetic approaches. 

Job Duties

• Maintain an organized daily electronic laboratory notebook.
• Regularly meet with Dr. Tran to discuss their work.
• Present results in professional forums (seminars, meetings, and conferences) .
• Publish findings in peer-reviewed journals.
• Perform assigned general laboratory chores.

Minimum Qualifications

  • MD or Ph.D. in Basic Science, Health Science, or a related field.
  • No experience required.

Preferred Qualifications

• Strong academic training in genetics and neurobiology 
• Demonstrated interest in vision science, neurodegeneration, and/or axon regeneration 
• Experience in animal surgery, immunohistochemistry, and molecular biology
• Experience in bioinformatics and single-cell genomics a plus

 

 

 

 

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

 7942

CA; PD