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Title:  Postdoctoral Associate - Alzheimer's Gene Therapy

Division:  Neuroscience
Schedule:  Monday - Friday 8:00 a.m - 5:00 p.m or as directed
Work Location:  Houston, TX
Salary Range:  Up to $63,000
FLSA Status:  Exempt
Requisition ID:  7136

Summary

The Jankowsky lab seeks a postdoctoral fellow to develop gene therapy for Alzheimer's disease. We have identified peptide variants that prevent and reverse amyloid formation. By vectorizing these peptides for viral delivery into the brain, we reduce plaque pathology in mouse models of AD (Park et al., Mol. Ther., 2021, PMID 33647457). We now want to examine how dosing, route, and timing of treatment influence efficacy, with particular emphasis on identifying treatments remain effective after disease onset. Future studies will apply the same strategy against tau by identifying sequence variants which prevent aggregation and can be vectorized for viral delivery. We seek a motivated candidate who is intellectually and experimentally flexible enough to advance these two projects simultaneously. Researchers will work as part of a team combining mouse genetic engineering, viral circuit manipulation, neurohistology, and basic biochemistry to understand Alzheimer's pathogenesis and develop potential treatments. You can learn more about our lab and ongoing projects at our website: https://www.bcm.edu/research/labs-and-centers/faculty-labs/joanna-jankowsky-lab.

Job Purpose

Postdoctoral Associates are trainees working in an apprenticeship mode in preparation for a career as a scientific professional.

Job Duties

  • Design and conduct research experiments.
  • Select and determine appropriate research procedures.
  • Collect, compile and analyze data.
  • Conduct literature searche and summarize information needed for particular studies.
  • Document and interpret results of experiments.
  • Prepare experimental results for publication and oral presentation

Minimum Qualifications

  • MD or Ph.D. in Basic Science, Health Science, or a related field.
  • No experience is required.

 

 

 

 

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

 7136

CA; PD