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Title:  Postdoctoral Associate

Division:  Neuroscience
Schedule:  Monday-Friday; 8:30 a.m. - 5:00 p.m.
Work Location:  Texas Medical Center, Houston, TX
Salary Range:  Up to $65,000
FLSA Status:  Exempt
Requisition ID:  6307

Summary


The laboratory of Dr. Andreas Tolias in the Department of Neuroscience at Baylor College of Medicine is seeking research associates at the level of postdoctoral fellows or at the level of Research Assistant Professors. The research associates will work collaboratively within a multi-disciplinary research team aimed at understanding the structure, function and computations of neocortical microcircuits and to decipher the canonical algorithms they implement. The specific goals of the research associates for these positions will be to use Patch-seq and multi-patching methods to study the logic of cell type diversity in the neocortex and map out the circuit diagram of the neocortex at the level of cell types across cortical areas and species. The fellows will work closely within an exciting collaborative team combining unique expertise in single cell RNA-sequencing, Patch-seq, multi-patching electrophysiology, functional multi-photon imaging, machine learning and computational neuroscience.  

You can learn more about our research at http://toliaslab.org and more specific information about the current project in recent publications from our lab:

F Scala, D Kobak, M Bernabucci, Y Bernaerts, CR Cadwell, JCastro, LHartmanis, X Jiang, S Laturnus, E Miranda, S Mulherkar, Z Tan, Z Yao, H Zeng, R Sandberg, P Berens, AS Tolias (2020). Phenotypic variation within and across transcriptomic cell types in mouse motor cortex Nature, doi: 10.1038/s41586-020-2907-3

Jiang X., Shen S., Cadwell C.R., Berens P., Sinz F., Ecker A.S., Tolias A.S. (2015). Principles of Connectivity among Morphologically Defined Cell Types in Adult Neocortex. Science. Vol. 350 no. 6264 DOI: 10.1126

Cadwell CR, Palasantza A, Jiang X, Berens P, Deng Q, Yilmaz M, Reimer J, Shen S, Bethge M, Tolias KF, Sandberg R & Tolias AS (2016). Morphological, electrophysiological and transcriptomic profiling of single neurons using Patch-seq. Nature Biotechnology, 34(2), 199-203. doi: 10.1038/nbt.3445. Epub 2015 Dec 21.

Job Purpose

Postdoctoral Associates are trainees working in an apprenticeship mode in preparation for a career as a scientific professional.

Job Duties

  • Plan, direct and conduct specialized and advanced research experiments.
  • Evaluate and analyzes data.
  • Establish new research protocols and procedures.
  • Summarize research findings and publish results in research journals.
  • Responsible for laboratory operations.
  • Supervise research staff.

Minimum Qualifications

  • MD or Ph.D. in Basic Science, Health Science, or a related field.

Preferred Qualifications

  • Extensive experience using patch-clamp electrophysiology as their primary research tool.
  • Experience with both in vitro and in vivo preps, or in vitro patching under difficult conditions (dendrites, multiple simultaneous patches, etc.).

 


 

Other

  • The postdoctoral fellow will also have the opportunity to develop their own project on related topics.

 

 

 

 

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

 6307

PD; CA