Title:  Postdoctoral Associate

Division:  Neurosurgery
Schedule:  Monday-Friday; 8:00 a.m. -5:00 p.m.
Work Location:  Texas Medical Center, Houston, TX
Salary Range:  $52,704
FLSA Status:  Exempt
Requisition ID:  5121


The Department of Neurosurgery at Baylor College of Medicine is a multidisciplinary and highly collaborative environment with a strong emphasis on translating basic research findings into clinical practice. Baylor College of Medicine is located in the vibrant Texas Medical Center, which is home to multiple cutting edge research institutions and provides a rich, and stimulating environment conducive to intellectual development and nurtures a team science approach. The successful candidate will benefit from synergistic collaborations with leading experts in chromatin biochemistry, cancer stem cells, drug development and neuro-oncology in the Houston area and beyond.

Job Purpose

A Postdoctoral position is available in the laboratory of Dr. Jamie Anastas, Assistant Professor in the Department of Neurosurgery and at the Center for Cell and Gene Therapy at Baylor College of Medicine. The Postdoc will be an integral member of our growing research team and will perform scientific research and develop next generation of therapies for brain tumors. Research in the Anastas lab primarily focuses on chromatin regulation in pediatric high grade glioma, a class of rare but aggressive brain tumors harboring frequent mutations in genes encoding histones (H3K27M and H3G34R/V). Future studies will employ a suite of genomic (RNAseq, chIPseq, CUT&RUN, etc.) and molecular analyses to reveal how chromatin dysregulation promotes pHGG tumorigenesis on a mechanistic level and will be aimed at identifying new therapeutic targets. We will also apply high-throughput pharmacogenetic screens to identify novel combinatorial therapies to overcome acquired and intrinsic drug resistance in childhood cancers. Learn more about the lab and our research here: www.anastaslab.org

Job Duties

  • Plans, directs and conducts specialized and advanced research experiments.
  • Evaluates and analyzes data.
  • Establishes new research protocols and procedures.
  • Summarizes research findings and publish results in research journals.
  • Responsible for laboratory operations.
  • Supervises research staff.

Minimum Qualifications

  • Ph.D. (or equivalent) in biomedical sciences, highly motivated and career-oriented.
  • Strong background in cancer biology, molecular biology, and genomics.

Preferred Qualifications

  • Previous experience in animal models and experience with stereotactic rodent surgery is highly preferred.
  • Previous experience in NGS technologies such as RNAseq, chIP-seq, ATACseq is ideal, but not required.


  • Applicants should submit a cover letter stating research experience and interest, a CV, and a list of 3 referees as a single PDF file.





Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.