Title:  Postdoctoral Associate

Division:  Pathology
Schedule:  Monday - Friday, 8:00 a.m. - 5:00 p.m.
Work Location:  Texas Medical Center, Houston, TX
Salary Range:  Up to $53,076
FLSA Status:  Exempt
Requisition ID:  4102

The Center for Drug Discovery (https://www.bcm.edu/research/centers/drug-discovery) is a strategic research center established at Baylor College of Medicine in Houston, Texas. We are seeking highly-motivated, organized and enthusiastic Postdoctoral Fellows contributing to the research in the study of the chemical features that facilitate passage across the blood-testis barrier using animal model and LC-MS-based approaches. The center is well equipped with UHPLC-Q Exactive MS and Thermo Quintus (triple quadruple) instruments to conduct LC-MS-based untargeted and targeted metabolomics. Analysis of uptake data for many highly diverse chemical structures will yield predictive rules to inform the development of male contraceptives and other drugs that must accumulate in the male genital tract. Baylor College of Medicine is located in the world-renowned Texas Medical Center and offers a highly interactive environment and a strong infrastructure for research and career development.

Job Purpose

Postdoctoral Associates are trainees working in an apprenticeship mode in preparation for a career as a scientific professional.

Job Duties
  • Plan, design and conduct animal experiments, especially on drug metabolism & tissue distribution.
  • LC-MS method development and sample preparation, and data analysis.
  • Perform cytotoxicity assays
  • Document and interpret results of experiments and report to principal investigators.
  • Conduct literature searches and summarize information in an appropriate format for a particular study.
  • Help to write and prepare manuscripts
  • Oversee the maintenance of lab equipment and environment.
  • Performs other job related duties as assigned.
Minimum Qualifications
  • Education Required: MD or Ph.D in Basic Science, Health Science, or a related field.
  • Experience Required: None Required.
  • Certification/Licenses/Registration: None Required.
Preferred Qualifications
  • Experience in animal surgery and drug tissue distribution.
  • Prior experience with transgenic animal models and experience with human primary hepatocytes and isolation of mouse primary hepatocytes.
  • Skilled in administrating drugs in mouse via IV, IP or oral gavage.

Core Competencies

  • Builds a logical approach to address problems or opportunities or manage the situation at hand by drawing on own knowledge and experience base and calling on other references and resources as necessary.
  • Aware of the industry within which Baylor College of Medicine operates, using knowledge of the organization's position in the marketplace to enhance competitive advantage.
  • Demonstrates knowledge of internal client needs, both current and future; addresses complaints, makes realistic commitments, and effectively communicates needs.
  • Willingly cooperates and works collaboratively towards solutions which generally benefit all involved parties; works cooperatively with others to accomplish company objectives; promotes collaboration and partnerships.
  • Accepts full responsibility for self and team, confronts problems quickly and builds commitment to organizational success.
  • Maintains channels of communication; effectively provides verbal communication and exhibits good listening skills; provides concise, complete, and professional information to others.

Functional Competencies

  • Conduct research and development activities to develop new products, technologies and applications.
  • Operates and maintains laboratory equipment to support research, operations and technical support.
  • Develops new technology solutions based on innovative designs which provide outstanding technology delivery for customers and enable market expansion.
  • Ensures health and safety standards are world class, achieving and exceeding all legislative requirements.


Core Competencies
Analytical Thinking/Problem Solving
Industry Knowledge
Client Service
Functional Competencies
Education Resources and Knowledge
Technical Depth
Academic Regulatory Knowledge





Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.