Title:  Postdoctoral Associate

Division:  Pediatrics
Schedule:  Monday - Friday, 8:00 a.m. - 5:00 p.m.
Work Location:  Texas Medical Center, Houston, TX
Salary Range:  $52,704 - $57,528
FLSA Status:  Exempt
Requisition ID:  3365

The Sheehan lab's research focus is on developing novel treatments for patients living with sickle cell disease (SCD). We apply genomics and transcriptomics to the questions of fetal hemoglobin induction and clinical severity in SCD. We have access to thousands of genomic samples with extended phenotypic information. After genomic associations are identified by our bioinformatics collaborators, the Sheehan Lab validates the associations with functional studies in primary cell culture and animal models. Transcriptomic data related to fetal hemoglobin response to hydroxyurea has already been analyzed, and candidates identified. These candidates need to be validated functionally in cell lines and then in primary erythroid culture.

Job Duties
  • Design and carry out experiments with minimal input
  • Maintain laboratory notebook and all experimental data in a manner understandable to others
  • Analyze data with minimal input
  • Write abstracts and manuscripts with input from PI
  • Review relevant literature in the field, and remain current
  • Attend weekly lab meetings and Hematology research meetings; present project at least quarterly; attaned and present at national meetings annually
Minimum Qualifications
  • Education Required: Ph.D in Basic Science, Health Science, or a related field.
  • Experience Required: None Required.
Preferred Qualifications
  • Two years experience.
  • Must have a strong background in molecular biology techniques such as shRNA knockdown, CRISPR/Cas9, western blot, RT q-PCR and tissue culture techniques.
  • Experience with rodent models a plus.





Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.