Title:  Postdoctoral Associate

Division:  Medicine
Schedule:  Monday - Friday, 8 a.m - 5 p.m
Work Location:  Texas Medical Center, Houston, TX
Salary Range:  Up to $50,004
FLSA Status:  Exempt
Requisition ID:  2398
Job Purpose

Postdoctoral Associates are trainees working in an apprenticeship mode in preparation for a career as a scientific professional

Job Duties

A full-time Postdoctoral Associate position is available immediately in the Kaochar laboratory at Baylor College of Medicine. We are seeking a highly motivated and skilled scientist to oncogenic signaling pathways in prostate cancer. The preferred candidate will be expected to have strong conceptual and experimental background in biochemistry as well as molecular biology, specifically in mammalian cells. Prior experience in the structure biology will be highly beneficial. Candidates must have at least one first-author publication (or article in press) in a high-impact journal and must demonstrate potential and commitment to become self-funded investigators under proper guidance.

Candidate will be expected to:
• Design experimental plans, lead study execution, analyze experimental data, generate laboratory protocols, and prepare manuscripts with minimum supervision from senior team leads.
• Troubleshoot and solve difficult problems in the design/execution and development of projects.
• Perform cell/tissue culture and determine/quantify cell viability.
• Isolate, purify and analyze RNA, DNA and protein including hybridization, gel electrophoresis, ECL imaging, PCR reactions, quantitative RT-PCR assays, etc.
• Perform molecular cloning, transformation, site-specific mutagenesis and transfection of plasmids.
• Perform stable and transient knockdown of targets of interest via siRNA/shRNA, CRISPR, lentiviral constructs, etc.
• Experience in protein expression in insect cells, structure-based drug design, and/or biophysics will be an advantage.
• Maintain accurate, detailed records of experimental data and protocols.

The candidate must be highly motivated to participate in rigorous and innovative research programs, and possess excellent work ethic and team spirit: be able to work independently and efficiently and collaborate closely with members of the group and other labs on joint projects. Fluent spoken English is essential.

Salary will be according to NIH guidelines. Candidate will be expected to apply for extramural funding.

Environment and opportunities: Baylor College of Medicine is a pioneer in the field of gene regulation, steroid receptors and their transcriptional coactivators, providing a rich scientific environment with many unique and unparalleled opportunities for collaborative research.

Interested candidates should submit a detailed CV, a cover letter explaining their relevant work experience, and 3 letters of supports including one from graduate thesis advisor to Dr. Salma Kaochar (kaochar@bcm.edu).

Minimum Qualifications

Education: Ph.D in Basic Science, Health Science, or a related field.

Experience: None required.





Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.