Title:  Postdoctoral Associate

Division:  Molecular and Human Genetics
Schedule:  Monday-Friday; 8:00am-5:00pm
Work Location:  Texas Medical Center, Houston, TX
Salary Range:  Hiring up to $54,756
FLSA Status:  Exempt
Requisition ID:  2128

Human Neuronal Differentiation Core (HNDC) is looking for a highly motivated Postdoctoral Scholar to join a research program investigating the molecular basis of neurodevelopmental and neurodegenerative disorders. HNDC supports studies of multiple research groups including those supported through the Intellectual and Developmental Disabilities Research Center (IDDRC). We are using directed differentiation and direct conversion of human pluripotent stem cells (embryonic and patient-derived induced pluripotent stem cells) for application of a wide range of molecular and genetic modifiers to human neurons and elucidation of underlying regulatory gene networks behind the cell phenotype. We are using 2D and 3D models and investigating contributions of various cells types in neural disease.

Job Purpose

HNDC is part of the Department of Molecular and Human Genetics, an internationally recognized department at Baylor College of Medicine. The core facilities are at the Neurological Research Institute of the Texas Children's Hospital, a multidisciplinary and extremely dynamic research environment with state-of-art infrastructure (https://nri.texaschildrens.org/core-facilities). In order to support the ongoing projects, the selected candidate will work directly with students and postdocs to design and conduct electrophysiology (patch-clamp and MEA) and calcium imaging experiments on human neurons cultured in 2D and 3D conditions.

Job Duties
  • Planning and performing advanced research experiments.
  • Establishing new research protocols and procedure.
  • Writing reports on analysis of acquired data.
  • Summarizing findings and assisting with figures for grant proposals and manuscripts.
  • May be responsible for laboratory management.
  • May supervise research staff.
Minimum Qualifications
  • Education: Ph.D in Basic Science, Health Science, or a related field.
  • A preference will be given to applicants with the following experience: neuronal cultures and organotypic slices, immunohistochemistry, fluorescent microscopy, whole cell patch-clamping, multi-electrode array recordings and calcium imaging.
  • A strong interest in and research training relevant to the areas of stem cell biology and neural development.

Essential personal qualities important for this job include sense of responsibility, excellent organizational skills, clear and effective verbal/written communication, interest in working in a dynamic setting with various groups, and unfailing desire to understand the brain.





Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.