Title:  Postdoctoral Associate

Division:  Neuroscience
Schedule:  Monday - Friday; 8:00 am - 5:00 pm
Work Location:  Baylor Main Campus, Houston, TX
Salary Range:  Up to $50,004
FLSA Status:  Exempt
Requisition ID:  1072

Postdoctoral Associate dedicated to use single-cell RNA-sequencing and related genetic tools to probe and define the cellular constituents of brain circuits in mice, macaque and human.

Job Purpose

The laboratory of Dr. Xiaolong Jiang in the Department of Neuroscience at Baylor College of Medicine and Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital is seeking applicants for the postdoctoral research position. The postdoctoral associate will work collaboratively within a multi-disciplinary research team aimed at understanding the cellular constituents of brain circuits in both health and diseases. The specific goals of this position will be to use patch clamp recordings, single-cell RNA-sequencing, machine learning, and sophisticated genetics tools to decipher cellular constituents of brain circuits across cortical areas and species with molecular, electrophysiological, and functional annotations.  

Job Responsibilities
  • Plans, directs and conducts specialized and advanced research experiments.
  • Evaluates and analyzes data.
  • May establish new research protocols and procedures.
  • Summarizes research findings and publish results in research journals.
  • May be responsible for laboratory operations.
  • May supervise research staff.
Minimum Qualifications

Education: Ph.D in Basic Science, Health Science, or a related field.

Experience: None required.

Preferred Qualifications

Experience: The ideal applicant should have genetic background with the experience in single-cell RNA-sequencing and bioinformatics analyses of large sequencing datasets, and even developing new bioinformatic methods if necessary. The experience in in vitro whole-cell patch recoding is preferred


You can learn more about our research at https://nri.texaschildrens.org/faculty/xiaolong-jiang-phd and more specific information about the current project in recent publications from out lab:

Jiang X, Shen S, Cadwell CR, Berens P, Sinz F, Ecker AS, Patel S & Tolias AS (2015). Principles of Connectivity among Morphologically Defined Cell Types in Adult Neocortex. Science. Vol. 350 no. 6264 DOI: 10.1126

Cadwell CR,  Palasantza A, Jiang X, Berens B, Deng Q, Yilmaz M, Reimer J, Bethge M,  Tolias KF, Sandberg R and Tolias AS. High-throughput morphological, electrophysiological and transcriptomic profiling  of single neurons. Nature Biotechnology. 2015 Dec 21.3. 

Scala F, Kobak D, Shan S, Bernaerts Y, Laturnus S, Cadwell CR, Hartmanis H, Castro J, Tan ZH, Sandberg S, Berens P, Jiang X*, Tolias AT*. Neocortical layer 4 in adult mouse differs in major cell types and circuit organization between primary sensory areas. BioRxiv. 2018, Dec.27; doi: //doi.org/10.1101/507293. Nature Communication. In press *co-corresponding authors

Cadwell CR, Scala F, Fahey PG, Kobak D, Sinz FH, Johnsson P, Li S, Cotton RJ, Sandberg S, Berens P, Jiang X*, Tolias AT*. Cell type composition and circuit organization of neocortical radial clones. BioRxiv. 2019, Jan.23; https://doi.org/10.1101/526681. *co-corresponding authors





Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.