Summary

Baylor College of Medicine is part of the world-renowned Texas Medical Center located in Houston, Texas, which offers a highly interactive environment and a strong infrastructure for research and career development. We are seeking highly skilled and motivated scientists with expertise in cell and molecular biology, biochemistry, immunology experience with macrophage and NK cells, to join the Center for Drug Discovery in a focused research effort on diseases impacting endometrial biology in the Department of Pathology & Immunology at Baylor College of Medicine. Using established cell systems, primary human tissues, 3-dimensional organoids, and high resolution microscopy, our group aims to uncover the biological mechanisms that underpin inflammatory diseases of endometriosis and adenomyosis. Our central vision is to improve the therapeutic options for endometrial-related diseases by developing a multidisciplinary team including academic and industrial drug discovery experts. The team, led by scientists with reproductive, genetics, biochemistry and drug discovery experience in academia and the pharmaceutical/biotech industry, is looking to recruit a highly motivated, skilled and career-oriented biochemist, molecular biologist, or geneticist.

Job Duties

• Develops and characterizes cellular models of kinase inhibitor profiles in endometrial cells and immune-derived cells.
• Uses standard 2-D and state-of-the-art 3D endometrial organoid cultures for the study of kinase inhibitor therapeutics on endometrial and immune cell interactions.
• Participates in early stage drug discovery in collaboration with scientists within the academic community, with a goal of bringing new treatments to patients with unmet medical needs.
• Develops and optimizes metabolic links between endometrial cells and cancer cells utilizing different novel metabolic techniques. 

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• PhD in immunology, reproductive biology, biochemistry, molecular biology, or a related discipline. 
• Published evidence of experience with the following : metabolic profiling analysis of different tissue/cell lines.
• Laboratory skills with molecular biology, biochemistry and metabolic data collection, analysis, interpretation.
• Experience with immune cells or tissues obtained from mouse models (naïve or mouse knockouts).
• A strong track record with excellent interpersonal skills and ability to work in a team environment. 
• ->3 years of hands-on laboratory experience in immunology, reproductive biology, biochemistry, molecular biology, metabolism or a related discipline and/or a related field and a track record of quality publications and/or patents in these areas.
• Experience with one or more of the following: protein production and purification, molecular biology and vector construction, metabolic and/or proteomic characterization and analysis, synthetic chemistry, and/or generation and analysis of mouse knockouts.
• Excellent interpersonal skills and an ability to work in a team environment. This position will require a person who can work independently and consult the literature to guide scientific efforts.