Summary

The lab is investigating the pathogenesis of myeloproliferative neoplasms (MPN), a group of chronic leukemias caused by gene mutations that are acquired in hematopoietic stem cells. The Postdoctoral Associate role is to investigate the molecular mechanisms of how Dnmt3a mutations collaborate with JAK2-V617F to accelerate conversion from clonal hematopoiesis to MPN. The lab is also studying how JAK2-V617F mutant stem cells gain resistance to therapeutic agents currently used to treat patients with MPN, such as tyrosine kinase inhibitors and interferon-α.

An enthusiastic postdoctoral associate who will work on independent and collaborative projects, and who will contribute to the vibrant and team-oriented laboratory environment. The Postdoctoral Associate is expected to drive and take ownership of their research project, design and perform biological experiments with rigor, be highly organized and communicative, and maintain high work ethics. Recent graduates interested in pursuing an independent academic career are welcome to apply for this position. 

For more information: 

https://www.bcm.edu/people-search/ctirad-skoda-174296

Job Duties

• Designs, optimizes, and executes research experiments to answer questions related to research projects.
• Works on experimental design.
• Analyzes data and results.
• Conducts data interpretation independently (with guidance from the PI or other lab members).
• Works collaboratively with other lab members, senior researchers, and faculty members at the departmental or inter-institutional levels. 
• Manages time and multiple projects efficiently while prioritizing deadlines and projects.
• Assists PI in training and mentoring research staff and undergraduate and graduate students as appropriate.
• Communicates their findings with other scientists at local, national, and international scientific conferences.
• Presents and prepares data into figures.
• Assists in written project updates and oral presentations that includes lab meetings, journal clubs to support manuscript writing for publication and grant proposals. 

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• MD or Ph.D. in Molecular Biology, Cell Biology, Biochemistry, or Immunology.
• Strong background in molecular biology, cellular biology, biochemistry, or cancer biology is desirable.
• Previous experience with CRISPR technology and/or CRISPR screens will be considered as an advantage.
• Be willing to work with mice and/or be comfortable at mouse handling.
• Good interpersonal and communication skills.
• Experience in presenting at national or international meetings.