Summary

The Hyser Lab in the Department of Molecular Virology and Microbiology is seeking a Postdoctoral Candidate for a 6 months position. The candidate needs to have expertise in molecular virology and live calcium imaging with specific experience in rotavirus, caliciviruses, enteroviruses, adeno-associated virus transduction, and computational analyses of live calcium imaging studies. The main focus of this position will be to identify and characterize elementary calcium signals from viral ion channels. Prior experience with viroporins and calcium imaging is required.

Job Duties

•  Experimental Design & Execution:
  • Develops and optimizes protocols for live-cell calcium imaging to study virus-induced calcium signaling.
  • Performs molecular virology techniques, including virus propagation, titration, and genetic manipulation of rotavirus, caliciviruses, and enteroviruses.
  • Conducts AAV transduction experiments for gene delivery in relevant cell models.
• Data Acquisition & Analysis:
  • Captures high-resolution live calcium imaging data using advanced microscopy systems.
  • Applies computational tools and algorithms to analyze calcium signaling patterns and quantify elementary calcium events. 
  • Interprets data to identify functional properties of viral ion channels and their impact on host cell physiology.
• Research & Development:
  • Investigates the role of viroporins in viral pathogenesis and calcium homeostasis.
  • Designs experiments to characterize ion channel activity and its contribution to viral replication and cell signaling.
  • Collaborates with team members to integrate findings into broader research objectives.
• Documentation & Reporting:
  • Maintains accurate laboratory records and prepare detailed reports of experimental results.
  • Contributes to manuscript preparation and presentation of findings at internal meetings. 

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Ph.D. in Basic Science, (Molecular Biology or Molecular Virology preferable).
• Prior experience with viroporins and calcium imaging techniques.
• Strong background in molecular virology and computational analysis of imaging data.
• Ability to work independently and collaboratively in a fast-paced research environment.