Summary

The Meng lab in the Department of Pediatrics, Section of Neurology, is offering a postdoctoral positions to study neurological disorders using brain organoids derived from human induced pluripotent stem cells (hiPSCs). The Meng lab integrates brain organoid models with CRISPR-Cas9-based genetic screening, antisense oligonucleotide (ASO)-mediated mRNA modification, single-cell RNA sequencing, confocal live imaging, and biochemical assays to explore the mechanisms underlying neurological disorders and develop novel gene therapies. Postdocs will receive comprehensive training in working with hiPSCs-derived brain organoids and engage in interdisciplinary research.

For more information about the PI, please check: https://www.texaschildrens.org/duncan-nri/faculty/xiangling-meng-phd

Job Duties

• Works independently and collaboratively to carry out assigned research projects.
• Gains comprehensive knowledge in the related field.
• Collects, compiles, analyzes data, and report to PI.
• Prepares manuscripts and other reports under the guidance of the PI.
• Applies for grant opportunities when appropriate.
• Maintains laboratory operations.
• Contributes to the training of students and other trainees. 

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Demonstrated ability and strong motivation to lead research projects.
• Previous experience in Neuroscience field.
• Additional desired (but not required) skills: CRISPR screening or drug screening, gene editing, NGS technologies such as RNAseq, chIP-seq, ATACseq, and advanced imaging