Summary

The laboratory of Dr. Leo Luznik at Baylor College of Medicine is seeking a highly motivated Postdoctoral Fellow to join a dynamic and translational research team focused on dissecting the immune microenvironment in acute myeloid leukemia and post-allogeneic hematopoietic cell transplantation. Our work investigates mechanisms of T cell dysfunction, immune escape, and clonal evolution leading to leukemia relapse, with the goal of developing novel immunotherapeutic strategies.

 The fellow will have access to cutting-edge tools including genetically engineered mouse models, single-cell multi-omics (scRNA-seq, CITE-seq, CyTOF), and patient-derived samples from institutional trials. This position is ideal for candidates passionate about tumor immunology, hematologic malignancies, and translational research.

Environment & Mentorship:

The Luznik Lab offers a supportive, collaborative environment with strong mentoring. Postdocs will benefit from individualized career development plans and opportunities to lead high-impact projects that bridge basic and translational research. The lab is part of a vibrant research community within Baylor College of Medicine and the Texas Medical Center, with ample opportunities for collaboration and career advancement. 

Job Duties

• Leads projects focused on immune profiling and mechanistic dissection of immune evasion pathways in AML using murine models and patient samples.
• Designs and performs experiments involving flow cytometry, T cell functional assays, bone marrow transplantation, and in vivo drug testing.
• Integrates single-cell transcriptomic and proteomic data to identify novel immunoregulatory targets.
• Collaborates with a multidisciplinary team including computational biologists, clinicians, and immunologists.
• Presents research at internal and external meetings; prepare manuscripts and contribute to grant applications.
• Supervises junior trainees and contribute to maintaining a collaborative and productive lab culture. 

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Ph.D. in immunology, cancer biology, molecular biology, or related field (MD/PhD candidates also welcome).
• Strong publication record in peer-reviewed journals.
• Experience with mouse models and multicolor flow cytometry.
• Expertise in tumor immunology, especially T cell biology, immune tolerance, or stem cell transplantation.
• Familiarity with single-cell technologies (scRNA-seq, CITE-seq, ATAC-seq).
• Experience in leukemia biology or hematopoietic stem cell systems.
• Excellent communication, teamwork, and organizational skills.