Title:  Postdoctoral Associate - RNA Biology

Summary

Postdoctoral positions are available in Furqan Fazal’s lab in the Department of Biochemistry and Molecular Biology to study the organization of RNAs within cells. The Fazal lab is a young laboratory focusing on systematically interrogating the subcellular transcriptomes of mammalian cells and characterizing the scope, regulation, and function of subcellular localization, particularly at the systems and organismal level. We use a variety of biochemical, biophysical, imaging, genomic and computational approaches to investigate the sequence-function relationship dictating RNA localization.

Fazal’s lab interests span from computational to wet-lab work, though the ideal candidate should have experience in molecular biology, RNA biology, cell biology, and/or informatics.

Recent relevant publications from the principal investigator include:

• Atlas of Subcellular RNA Localization Revealed by APEX-seq. Cell 2019.
• RNA Structure Maps Across Mammalian Cellular Compartments. Nature Structural & Molecular Biology 2019.
• RNA-GPS Predicts SARS-CoV-2 RNA Residency to Host Mitochondria and Nucleolus. Cell Systems 2020.
• Subcellular Spatial Transcriptomes: Emerging Frontier for Understanding Gene Regulation. CSHL Symposia of Quantitative Biology 2019.

Visit the BCM website (https://www.bcm.edu/people-search/furqan-fazal-72901) for more information about our lab.

Job Purpose

Postdoctoral Associates are trainees working in an apprenticeship mode in preparation for a career as a scientific professional.

Job Duties

• Use a variety of biochemical, biophysical, imaging, genomic and computational approaches to investigate the sequence-function relationship dictating RNA localization.
• Assist with graduate student training and mentorship.
• Present research findings at institutional, regional, and/or national scientific meetings.
• Maintain good communication with lab leader and members.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience.

Preferred Qualifications

• PhD degree in biochemistry, bioengineering, biophysics, or related field preferred.
• RNA biology, genomics, genetics, informatics.