Baylor College of Medicine and The Lester and Sue Smith Breast Center:

Baylor (www.bcm.edu) is recognized as one of the nation’s premier academic health science centers and is known for excellence in education, research, and healthcare and community service. Located in the heart of the world's largest medical center (Texas Medical Center), Baylor is affiliated with multiple educational, healthcare and research affiliates (Baylor Affiliates).

The Lester and Sue Smith Breast Center at Baylor College of Medicine is a stand-alone, multi-disciplinary academic unit focusing on breast cancer research and patient care. The stand-alone and multi-disciplinary nature and the focus on a single cancer type distinguish the LSSBC from all other academic units in the United States. The center integrates clinical trials, informatics, technology, and cancer biology for the sole purpose of conquering breast cancer and improving patient care. We are one of the few recipients of the NIH Specialized Program of Research Excellence (SPORE).

The basic and translational research at Breast Center covers areas of cancer stem cells, tumor microenvironment and metastasis. Our scientists have continuously made breakthroughs in understanding how breast cancer disseminates and becomes resistant to therapies. The close collaboration with clinicians enables smooth translation of lab studies at the bench to clinical treatment at the bedside. We also work to engage the community for a more concerted action against breast cancer.

Summary

The Lester and Sue Smith Breast Center at Baylor College of Medicine is looking to recruit a talented scientist focusing on the areas of expertise in molecular biology, animal studies, and preclinical therapeutic development.

Job Duties

• Prepares and conducts laboratory research experiments specific to protein synthesis and quality control in tumor cells and the tumor microenvironment during tumorigenesis, metastasis, and therapeutic resistance
• Collects, compiles and analyzes data focusing on mechanisms of resistance to eIF4A inhibition
• Conducts literature searches and summarizes information in an appropriate format for a particular study.
• Documents results of experiments.
• Selects, evaluates and applies techniques used in routine research.
• Seek external funding via grants applications/submissions.
• Engage in teaching graduate or medical students
• Involve in departmental committee duties
• Train and supervises less experienced research staff such as graduate students and postdocs.
• Study how certain estrogen receptor alpha (ER) fusion proteins that arise in metastatic breast cancer patients due to ESR1 (gene encoding ER) chromosomal translocations drive breast cancer progression and metastasis
• Collaborate with scientists out of the lab for multidisciplinary study
• Develop new model and technique to support the cancer-related research in the lab
• Advise junior scientists and provide guidance on their projects

Minimum Qualifications

Education: Doctoral degree in a biomedical science.