Summary

A Postdoctoral Fellow position is available in the laboratory of Dr. Dongyin Guan in the Department of Medicine at Baylor College of Medicine.

The Guan lab’s research focuses on using multidisciplinary approaches for functional multi-omics to identify and characterize key regulators to understand environment-gene interactions in metabolic diseases and cancer. The established platforms include GRO-seq, RNA-seq, ChIP-seq, ATAC-seq, CRISPR-seq, single-cell RNA/ATAC-seq, microC, machine learning, sophisticated mouse genetic tools, and an ex vivo tissue culture system from patients. Applicants with backgrounds in Physiology, Molecular Biology, and Bioinformatics are preferred, although the specific area of expertise is less important than a drive to perform interdisciplinary research at the cutting edge. The candidate needs to have a Ph.D. from an accredited institution, an excellent publication record, efficient time management skills, and a strong work ethic. Most importantly, the candidate needs to be passionate about solving unanswered questions in metabolic disorders, cancer biology, or circadian rhythms. You will lead projects, design experiments, collaborate with other scientists to accomplish research goals, write papers, and contribute to grant writing. This position is funded by a generous Cancer Prevention Research Institute of Texas (CPRIT) award and NIH funding. Baylor College of Medicine is a top tier Medical School and Biosciences Graduate School with a long history of innovation and current leadership in the biomedical sciences. Baylor College of Medicine is located in the center of the world's largest life science complex in the heart of the fourth most populous city in America. It is within walking distance of numerous educational and biomedical research institutions (e.g. Rice University & MD Anderson Cancer 

Job Duties

• Prepare samples and perform validation studies for omics analysis using genetically modified mouse models. 
• Performs functional analysis to determine the role of identified hits.
• Perform molecular biology experiments to determine the underlying molecular mechanisms.
• Train new and junior lab members and students.
• Writes manuscript with the PI to report the findings. 
• Accurately documents experiments to ensure that work can be replicated by others. 
• Performs other job-related duties as assigned.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.

Preferred Qualifications

• PhD.
• Experience in metabolism, cancer biology, epigenetics, or bioinformatics.